Ro’s Super Bowl Debut With Serena Williams Tackles GLP-1 Stigma

Ro and tennis legend Serena Williams are bringing the GLP-1 conversation to the Super Bowl.

Ro, a direct-to-consumer healthcare business that sells GLP-1 medications including Ozempic, Wegovy, and Zepbound, is making its Super Bowl debut with an ad starring its brand ambassador, Williams. The commercial will air nationally during NBC’s broadcast and kick off a new campaign, “Healthier on Ro,” spanning TV, paid social, and out-of-home takeovers in cities across the U.S.

The goal behind “Healthier on Ro” is to destigmatize the drug and promote its other health benefits beyond weight loss. It continues Ro’s partnership with Williams that began in August, with an ad in which the sports icon publicly shared that she uses a GLP-1 drug.

At the time, Ro enlisted Williams to “dispel the myth that taking weight loss medications is cheating,” said Saman Rahmanian, Ro’s co-founder and chief product officer. The company wanted to show that if even an elite athlete such as Williams benefited from GLP-1s, “it’s not a shortcut,” he added.

Williams’ husband, entrepreneur and Reddit co-founder Alexis Ohanian, is an investor in Ro and serves on its board. 

With its Super Bowl 60 ad, Ro is tackling another misconception: “that weight loss medications are only for vanity. We know that the value of GLP-1s is more than skin deep,” Rahmanian told ADWEEK.

In the spot, Williams shares the health benefits she’s experienced since taking GLP-1s, including losing 34 pounds in a year, reduced knee joint stress, steady blood sugar, and lowered cholesterol. 

As in her first campaign with Ro, Williams is also shown literally using the product – injecting it with a pen, ordering it via a mobile app, and promoting the new pill version.

Developed by Ro’s internal creative team and production company Young Hero, the spot uses a bright color scheme and high-energy soundtrack – “Riot Rhythm” by Sleigh Bells – to “convey what it feels like to be on Ro,” Rahmanian said.

Hot this week

The Bella Hadid Guide To Fashion-Month Outerwear

In 2026, we finally have some good news on...

Scary Rogue AI Drone Sci-Fi Action Thriller Film ‘Dragn’ Official Trailer

Scary Rogue AI Drone Sci-Fi Action Thriller Film 'Dragn'...

Here's How Animators Make Stop-Motion Masterpieces Like 'Wallace & Gromit' Come Alive

Aardman's iconic shows, shorts and feature films require painstaking...

‘Game of Thrones’ Movie in Development with Beau Willimon

Warner Bros. Pictures is developing a film that could...

Topics

The Bella Hadid Guide To Fashion-Month Outerwear

In 2026, we finally have some good news on...

Scary Rogue AI Drone Sci-Fi Action Thriller Film ‘Dragn’ Official Trailer

Scary Rogue AI Drone Sci-Fi Action Thriller Film 'Dragn'...

Here's How Animators Make Stop-Motion Masterpieces Like 'Wallace & Gromit' Come Alive

Aardman's iconic shows, shorts and feature films require painstaking...

‘Game of Thrones’ Movie in Development with Beau Willimon

Warner Bros. Pictures is developing a film that could...

ANiMPACT Standards presented at Cartoon Movie

03/03/2026 - Marking a major step towards lending more...

What Will Paramount-WBD Deal Mean for TV’s Premium Pioneer?

On today’s episode of “Daily Variety” podcast, Variety’s Michael...

Russia’s Pavilion at the Venice Biennale to Reopen This Year

After closing for the last two editions of the...
spot_img

Related Articles

Popular Categories

spot_imgspot_img